A devious serial killer lays siege to the city of Philadelphia, brutally sacrificing pretty young Catholic girls on the altar of insanity. As the body count rises, an exceptional investigating partnership struggles to stop him. Detective Jessica Balzano, Philly's Homicide Unit's newest rookie, is teamed up with the veteran cop Kevin Byrne, respected for his solve rate and known for his unorthodox methods. The pair, willing to do anything it takes to stop the bloody rampage, leads a chase for a twisted, demonical killer fueled by a sacrilegious fury.